Alli is the brand name for the drug orlistat. It is one of the most popular weight loss pills.
Orlistat is available as a prescription drug and also sold over the counter. It works by preventing the body from breaking down of some of the fat that people eat. When the intestines absorb less fat, weight loss may occur.
A review of 11 studies indicated that orlistat might increase weight loss by a small amount. The review found that those who took orlistat lost an average of 2.9 percent more weight than those who did not take the drug.
Orlistat may cause a change in bowel habits. People taking orlistat may experience side effects, such as diarrhea, stomach pain, and difficulty controlling bowel movements.
Caffeine is a stimulant found in coffee, tea, soft drinks, and chocolate. It is also often added to diet pills and supplements.
According to a study of 76 obese adults, people who had high caffeine intake saw a greater reduction in fat mass, weight circumference, and overall weight compared to those who had low caffeine intake.
Side effects of caffeine include jitteriness, increased heart rate, and trouble sleeping.
Glucomannan is a type of fiber supplement. It works by absorbing water in the gut, leading to a feeling of fullness that may prompt people to eat less.
Studies appear to be conflicting on whether glucomannan can aid in weight loss, however.
A 2005 study of 176 people indicated that glucomannan contributed to weight loss in healthy, overweight adults.
However, a more recent review of randomized control trials indicated that glucomannan did not appear to result in significant weight loss.
For those who do take glucomannan, side effects may include gas, diarrhea, and stomach pain.
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